Primary Identifier | MGI:101836 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 22029 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including enzyme binding activity; identical protein binding activity; and tumor necrosis factor receptor binding activity. Predicted to be involved in positive regulation of NF-kappaB transcription factor activity; regulation of signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to be active in cytoplasm. Is expressed in jaw and urinary system. Orthologous to human TRAF1 (TNF receptor associated factor 1). PHENOTYPE: Homozygous null mice exhibit abnormal T cell functionality. [provided by MGI curators] |