Primary Identifier | MGI:2183535 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 227929 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in regulation of cell adhesion. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cell cortex. Is expressed in metanephros. Orthologous to human CYTIP (cytohesin 1 interacting protein). PHENOTYPE: Mice homozygous for a null allele display impaired trafficking and/or cell adhesion of immune system cells. Mice homozygous for a reporter allele show normal immune cell development and function; however, mutant hematopoietic stems cells have impaired repopulating activity. [provided by MGI curators] |