| Primary Identifier | MGI:2150150 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 94229 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sodium,bicarbonate:chloride antiporter activity and sodium:bicarbonate symporter activity. Involved in regulation of short-term neuronal synaptic plasticity and visual perception. Acts upstream of or within several processes, including brain development; locomotory exploration behavior; and proton transmembrane transport. Located in several cellular components, including GABA-ergic synapse; basolateral plasma membrane; and dendrite. Is expressed in several structures, including gut; nervous system; sensory organ; and testis. Orthologous to human SLC4A10 (solute carrier family 4 member 10). PHENOTYPE: Mice with homozygous disruption of this gene exhibit reduced brain ventricle volume, reduced neuronal excitability, impaired pH regulation of neurons, and increased threshold to induced seizures. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
