| Primary Identifier | MGI:95674 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 14526 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables receptor ligand activity. Involved in several processes, including positive regulation of protein phosphorylation; positive regulation of transport; and regulation of intracellular signal transduction. Acts upstream of or within negative regulation of execution phase of apoptosis and positive regulation of gluconeogenesis. Located in cytoplasm and extracellular space. Is active in plasma membrane. Is expressed in several structures, including brain; gut; liver; and urogenital ridge. Human ortholog(s) of this gene implicated in Alzheimer's disease and prediabetes syndrome. Orthologous to human GCG (glucagon). PHENOTYPE: Mice homozygous for a knock-out allele exhibit islet alpha cell hyperplasia and increased body weight. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
