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Protein Coding Gene : Cers6 ceramide synthase 6
Primary Identifier  MGI:2442564 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  241447
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables sphingosine N-acyltransferase activity. Involved in ceramide biosynthetic process. Acts upstream of or within sphingolipid biosynthetic process. Located in endoplasmic reticulum. Is expressed in blastocyst; early embryo; genitourinary system; limb mesenchyme; and skin. Orthologous to human CERS6 (ceramide synthase 6).
PHENOTYPE: Mice homozygous for a knockout allele exhibit hind limb clasping, habituation deficit and altered lipid homeostasis. [provided by MGI curators]
  • synonyms:
  • Cers6,
  • MGI:2139372,
  • T1L,
  • CerS6,
  • expressed sequence AW544719,
  • Lass6,
  • similar to TRH1,
  • 4732462C07Rik,
  • LAG1 homolog, ceramide synthase 6,
  • RIKEN cDNA 4732462C07 gene,
  • AW544719,
  • ceramide synthase 6
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Disease

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