Primary Identifier | MGI:3606242 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 329416 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Acts upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. Orthologous to human NOSTRIN (nitric oxide synthase trafficking). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired retinal vascular angiogenesis, endothelial cell proliferation, endothelial cell migration and induced neovascularization. [provided by MGI curators] |