| Primary Identifier | MGI:1277193 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 14378 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glucose-6-phosphatase activity. Predicted to be involved in several processes, including gluconeogenesis; glucose 6-phosphate metabolic process; and regulation of insulin secretion. Located in endoplasmic reticulum. Is expressed in embryo; islets of Langerhans; and pancreas. Used to study type 1 diabetes mellitus. Orthologous to human G6PC2 (glucose-6-phosphatase catalytic subunit 2). PHENOTYPE: Mice homozygous for a disruption of this gene show a significant drop in fasting blood glucose. Females also show a significant drop in plasma triacylglycerol. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
