Primary Identifier | MGI:2135962 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 70231 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in several processes, including Golgi organization; establishment of protein localization to plasma membrane; and response to endoplasmic reticulum stress. Predicted to be located in Golgi medial cisterna; Golgi membrane; and endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including brain and retina nuclear layer. Orthologous to human GORASP2 (golgi reassembly stacking protein 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal growth retardation and male infertility associated with impaired spermatogenesis, asthenozoospermia, oligozoospermia, and abnormalities in acrosome formation and Golgi apparatus morphology. [provided by MGI curators] |