Primary Identifier | MGI:2385142 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 228019 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables histone acetyltransferase activity and mRNA methyltransferase activity. Acts upstream of or within fat cell differentiation and skeletal muscle tissue development. Located in cytoplasm and nucleus. Is expressed in several structures, including body cavity or lining; cerebral cortex; genitourinary system; respiratory system; and vertebral axis musculature. Orthologous to human METTL8 (methyltransferase 8, tRNA N3-cytidine). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced 3-methylcytidine (m3C) methyltransferases modification of mRNA. [provided by MGI curators] |