Primary Identifier | MGI:2654575 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 73649 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transmembrane ascorbate ferrireductase activity. Acts upstream of or within response to iron ion. Located in brush border membrane. Is expressed in several structures, including central nervous system; foregut; gonad; retina; and trachea. Orthologous to human CYBRD1 (cytochrome b reductase 1). PHENOTYPE: Mice homozygous for a knock-out allele show alterations in liver weight and liver iron content when fed an iron-deficient diet. [provided by MGI curators] |