Primary Identifier | MGI:1915674 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 108699 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ephrin receptor binding activity. Involved in ephrin receptor signaling pathway; motor neuron axon guidance; and regulation of axonogenesis. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Used to study Duane retraction syndrome. Human ortholog(s) of this gene implicated in Duane retraction syndrome. Orthologous to human CHN1 (chimerin 1). PHENOTYPE: Mice homologous for a null allele exhibit transient postnatal size reduction, abnormal gait and abnormal innervation of the spinal cord. [provided by MGI curators] |