Primary Identifier | MGI:95462 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 14029 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within limb morphogenesis. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; limb; limb bud; and sensory organ. Orthologous to human EVX2 (even-skipped homeobox 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased body weight, male infertility, short limbs, and abnormalities in phalanx, carpal bone and metacarpal bone morphology. [provided by MGI curators] |