| Primary Identifier | MGI:96201 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 15429 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within embryonic skeletal system development; neuron differentiation; and sensory perception of pain. Located in nucleus. Is expressed in several structures, including early embryo; embryo mesenchyme; genitourinary system; intestine epithelium; and nervous system. Orthologous to human HOXD1 (homeobox D1). PHENOTYPE: Mice homozygous for a reporter allele display abnormal cervical vertebrae. Mice homozygous for a knock-out allele exhibit abnormal nociceptor innervation of the skin, aberrant nociceptor axonal projections in the spinal cord, and deficits in pain sensitivity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
