Primary Identifier | MGI:1859652 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 53375 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in mitochondrial transport and mitochondrion organization. Located in mitochondrion. Is expressed in central nervous system; embryo; and retina. Orthologous to human MTX2 (metaxin 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete embryonic lethality by E9.5. [provided by MGI curators] |