Primary Identifier | MGI:88579 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 13067 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables heme binding activity. Acts upstream of or within hydrogen peroxide metabolic process and positive regulation of intrinsic apoptotic signaling pathway. Located in mitochondrion. Is expressed in embryo. Orthologous to human CYCTP (cytochrome c, testis, pseudogene). PHENOTYPE: Mice homozygous for a targeted null mutation exhibit reduced sperm counts, impaired fertilization and testicular atrophy due to a dysfunction of oxidative phosphorylation in the spermatocytes. [provided by MGI curators] |