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Protein Coding Gene : Cyct cytochrome c, testis

Primary Identifier  MGI:88579 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  13067
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables heme binding activity. Acts upstream of or within hydrogen peroxide metabolic process and positive regulation of intrinsic apoptotic signaling pathway. Located in mitochondrion. Is expressed in embryo. Orthologous to human CYCTP (cytochrome c, testis, pseudogene).
PHENOTYPE: Mice homozygous for a targeted null mutation exhibit reduced sperm counts, impaired fertilization and testicular atrophy due to a dysfunction of oxidative phosphorylation in the spermatocytes. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-2288,
  • cytochrome c, testis,
  • T-Cc,
  • Cyct

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For