| Primary Identifier | MGI:96603 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 16401 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables fibronectin binding activity. Acts upstream of or within several processes, including chorio-allantoic fusion; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and pericyte cell migration. Located in cell-cell junction and external side of plasma membrane. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autism spectrum disorder and pancreatic cancer. Orthologous to human ITGA4 (integrin subunit alpha 4). PHENOTYPE: Mice homozygous for disruptions in this gene exhibit embryonic lethality either due to failure of chorioallantoic fusion or cardiac abnormalities, including hemorrhage around the heart and defects in epicardium formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
