Primary Identifier | MGI:2442949 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 241514 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity. Predicted to be involved in positive regulation of dendritic spine maintenance; positive regulation of gene expression; and positive regulation of neuron projection development. Predicted to be located in several cellular components, including dendrite; growth cone; and neuronal cell body. Predicted to be active in nucleus. Is expressed in nervous system; tongue; and urogenital sinus. Used to study schizophrenia. Orthologous to human ZNF804A (zinc finger protein 804A). PHENOTYPE: Mice homozygous for a null allele exhibit impaired contextual memory, impaired spatial learning in female mice, impaired reference memory, decreased PPI in female mice, and decreased dendritic spine density in cortical and hippocampal neurons. [provided by MGI curators] |