Primary Identifier | MGI:1919111 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 71861 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ubiquitin protein ligase activity. Involved in protein polyubiquitination. Acts upstream of or within positive regulation of extrinsic apoptotic signaling pathway via death domain receptors. Orthologous to human ZSWIM2 (zinc finger SWIM-type containing 2). PHENOTYPE: Homozygous null males exhibit normal fertility. [provided by MGI curators] |