| Primary Identifier | MGI:105100 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 12388 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein domain specific binding activity and protein phosphatase binding activity. Involved in positive regulation of protein localization to cell-cell junction. Acts upstream of or within several processes, including glomerulus morphogenesis; positive regulation of protein metabolic process; and salivary gland development. Located in several cellular components, including adherens junction; apicolateral plasma membrane; and bicellular tight junction. Part of flotillin complex. Is expressed in several structures, including 4-8 cell stage embryo; alimentary system; central nervous system; eye; and metanephros. Human ortholog(s) of this gene implicated in blepharocheilodontic syndrome 2. Orthologous to human CTNND1 (catenin delta 1). PHENOTYPE: Mice homozygous for disruptions of this gene die shortly after birth and have morphological abnormalities of the salivary glands and lacrimal gland. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
