Primary Identifier | MGI:3605071 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 241525 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including negative regulation of erythrocyte clearance; negative regulation of erythrocyte differentiation; and protein localization to plasma membrane. Predicted to be located in nucleolus. Is expressed in forebrain. Orthologous to human YPEL4 (yippee like 4). PHENOTYPE: Homozygous knockout affects erythrocyte morphology and leads to increased red blood cell concentration, clearance rate, size and size variation and reduced deformability. [provided by MGI curators] |