| Primary Identifier | MGI:1929260 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 56428 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable membrane insertase activity. Involved in several processes, including lipid homeostasis; positive regulation of stem cell differentiation; and regulation of mitochondrial fusion. Acts upstream of or within several processes, including hematopoietic stem cell homeostasis; hepatocyte apoptotic process; and mitochondrial membrane organization. Located in mitochondrial outer membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut gland; integumental system; and liver and biliary system. Orthologous to human MTCH2 (mitochondrial carrier 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal mesoderm development, disorganized extraembryonic tissue, lack of amnion and chorion formation, decreased embryo size, and lethality at around E7.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
