| Primary Identifier | MGI:1342295 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 13046 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables lncRNA binding activity; mRNA binding activity; and translation initiation factor binding activity. Acts upstream of or within several processes, including mRNA splice site recognition; regulation of alternative mRNA splicing, via spliceosome; and spermatid development. Located in cytoplasm and male germ cell nucleus. Is expressed in several structures, including branchial arch; central nervous system; early embryo; musculature; and testis. Orthologous to human CELF1 (CUGBP Elav-like family member 1). PHENOTYPE: Homozygous disruption of this gene results in significant postnatal lethality, growth retardation, and impaired fertility in both sexes. Male infertility is caused by a blockage of spermiogenesis at stage 7 and increased germ cell apoptosis but is not fully penetrant. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
