Primary Identifier | MGI:1923036 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 75786 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable microtubule binding activity; microtubule plus end polymerase; and ribonucleoprotein complex binding activity. Acts upstream of or within several processes, including central nervous system myelin formation; dendritic spine maintenance; and learning. Located in dendrite; neuronal ribonucleoprotein granule; and perikaryon. Is expressed in several structures, including male reproductive gland or organ; nervous system; nose; respiratory system; and tooth. Orthologous to human CKAP5 (cytoskeleton associated protein 5). PHENOTYPE: Mice homozygous for a transgenic disruption of this gene exhibit decreased body size and cleft palate while a targeted null allele causes embryonic lethality in homozygotes and heterozygotes have decreased body temperature, abnormal retina outer nuclear layer, and abnormal embryo size [provided by MGI curators] |