Primary Identifier | MGI:1338829 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 18633 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in peroxisome organization and protein to membrane docking. Predicted to act upstream of or within protein import into peroxisome matrix. Located in peroxisomal membrane. Is expressed in head; tail; and trunk. Human ortholog(s) of this gene implicated in Peroxisome biogenesis disorder 8B and peroxisome biogenesis disorder 8A. Orthologous to human PEX16 (peroxisomal biogenesis factor 16). PHENOTYPE: Mice homozygous for a conditional allele activated in adipose tissue exhibit impaired cold tolerance, decreased energy expenditure, and increased diet-induced obesity. [provided by MGI curators] |