| Primary Identifier | MGI:1916742 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 75641 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-macromolecule adaptor activity. Involved in several processes, including fusion of sperm to egg plasma membrane involved in single fertilization; maintenance of protein localization in endoplasmic reticulum; and sperm-egg recognition. Acts upstream of or within several processes, including protein modification process; protein stabilization; and spermatid development. Located in endoplasmic reticulum membrane. Is active in membrane. Orthologous to human FREY1 (Frey regulator of sperm-oocyte fusion 1). PHENOTYPE: Homozygous null mutations in this gene result in male infertility due to failure of sperm-egg fusion. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
