| Primary Identifier | MGI:1309464 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 19099 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables kinesin binding activity and protein kinase binding activity. Involved in positive regulation of JNK cascade and regulation of CD8-positive, alpha-beta T cell proliferation. Acts upstream of or within several processes, including JUN phosphorylation; negative regulation of intrinsic apoptotic signaling pathway; and regulation of DNA-templated transcription. Located in several cellular components, including dendrite; dentate gyrus mossy fiber; and neuronal cell body. Is expressed in several structures, including early conceptus; genitourinary system; musculature; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1). PHENOTYPE: Homozygous mutation of this gene results in a decreased susceptibility to ischemic brain injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
