Primary Identifier | MGI:1933945 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 80976 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable SNARE binding activity; calcium ion sensor activity; and calcium-dependent phospholipid binding activity. Acts upstream of or within vesicle-mediated transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human SYT13 (synaptotagmin 13). PHENOTYPE: Homozygous null mice exhibit postnatal lethality with altered epithelial organization of the pancreas, impaired pancreas endocrine cell egression and increased alpha-to-beta-cell ratio. [provided by MGI curators] |