| Primary Identifier | MGI:2685553 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 100042784 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity. Predicted to be involved in several processes, including negative regulation of cell growth; positive regulation of fibroblast apoptotic process; and regulation of DNA-templated transcription. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Is expressed in embryo and head. Orthologous to human PRDM11 (PR/SET domain 11). PHENOTYPE: Mice homozygous for a null allele show increased cell numbers in bronchioalveolar lavages and changes in B cell, CD4+ T cell and neutrophil counts following ovalbumin airway challenge, and a small decrease in megakaryocytic progenitors and a small increase in hematopoietic progenitor cell proliferation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
