| Primary Identifier | MGI:1917186 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 241556 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transmembrane transporter binding activity. Acts upstream of or within several processes, including calcium-ion regulated exocytosis; hemostasis; and inflammatory response. Predicted to be located in cell periphery. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human TSPAN18 (tetraspanin 18). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a hemostasis defect, impaired histamine-induced von Willebrand Factor (vWF) release, and decreased susceptibility to induced thrombosis in vWF-dependent thrombo-inflammatory models. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
