Primary Identifier | MGI:2138856 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 241576 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables amyloid-beta binding activity. Acts upstream of or within receptor-mediated endocytosis and regulation of protein processing. Located in plasma membrane. Is expressed in cranial ganglion; dorsal root ganglion; and gut. Orthologous to human LDLRAD3 (low density lipoprotein receptor class A domain containing 3). PHENOTYPE: Homozygous knockout results in resistance to Venezuelan equine encephalitis virus (VEEV) infection. [provided by MGI curators] |