| Primary Identifier | MGI:1270840 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 13661 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in epithelial cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; female reproductive system; gut; salivary gland primordium; and urinary system. Orthologous to human EHF (ETS homologous factor). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced intestinal stem cells with impaired organoid formation capacity and shorter crypts of Lieberkuhn and small intestinal villi. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
