| Primary Identifier | MGI:88271 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 12359 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables aminoacylase activity and catalase activity. Acts upstream of or within several processes, including hydrogen peroxide catabolic process; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of DNA-binding transcription factor activity. Located in peroxisomal membrane. Is expressed in several structures, including alimentary system; early conceptus; heart; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including acatalasia; eye disease (multiple); lung disease (multiple); osteonecrosis; and pseudoxanthoma elasticum. Orthologous to human CAT (catalase). PHENOTYPE: Mice homozygous for disruptions in this gene display a generally normal phenotype although subtle abnormalities do occur in mitochondrial respiration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
