Primary Identifier | MGI:96661 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 16492 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential and voltage-gated potassium channel activity. Predicted to be involved in action potential and potassium ion transmembrane transport. Located in membrane. Is active in axon initial segment. Is expressed in brain; genital tubercle of female; heart; and hindlimb muscle. Orthologous to human KCNA4 (potassium voltage-gated channel subfamily A member 4). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and grossly normal; however, a small subset of mutants exhibit spontaneous seizure activity. [provided by MGI curators] |