Primary Identifier | MGI:1920274 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 73024 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable carbohydrate binding activity. Predicted to contribute to membrane insertase activity. Predicted to be involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of EMC complex. Is expressed in central nervous system; liver; lung; retina nuclear layer; and skeletal muscle. Orthologous to human EMC7 (ER membrane protein complex subunit 7). PHENOTYPE: Homozygous mice are not viable. Male heterozygous mice exhibited an increased anxiety-like response during stress-induced hyperthermia testing. [provided by MGI curators] |