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Protein Coding Gene : Aven apoptosis, caspase activation inhibitor
Primary Identifier  MGI:1921518 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  74268
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to be involved in negative regulation of G2/M transition of mitotic cell cycle and negative regulation of apoptotic process. Predicted to be located in membrane. Is expressed in several structures, including heart; liver; metanephros; spleen; and testis. Orthologous to human AVEN (apoptosis and caspase activation inhibitor).
PHENOTYPE: Mice homozygous for a reporter allele exhibit increased cell death in response to various apoptotic stimuli. [provided by MGI curators]
  • synonyms:
  • mAven-L,
  • 1700013A01Rik,
  • mAven-S,
  • 1700056A21Rik,
  • RIKEN cDNA 1700056A21 gene,
  • apoptosis, caspase activation inhibitor,
  • Aven,
  • RIKEN cDNA 1700013A01 gene,
  • MGI:1916615
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Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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