| Primary Identifier | MGI:101815 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 14260 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables SH3 domain binding activity. Acts upstream of or within several processes, including limb morphogenesis; positive regulation of cellular component organization; and ureteric bud invasion. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and limb bud. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human FMN1 (formin 1). PHENOTYPE: Homozygotes for spontaneous, irradiation-induced, and transgene-insertional mutations show severe syndactyly and oligodactyly of the feet, abnormal long bones (including radius-ulna fusions), and reduced or absent kidneys. Many mutants survive and breed. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
