Primary Identifier | MGI:1918563 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 71313 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including axoneme assembly; homeostasis of number of cells within a tissue; and vesicle organization. Is active in acrosomal vesicle; nucleus; and sperm head. Orthologous to human FSIP1 (fibrous sheath interacting protein 1). PHENOTYPE: Homozygous null males show partial globozoospermia, impaired spermiogenesis, abnormal sperm morphology, including misshapen head, flagella assembly failure, and disrupted acrosome vesicle, reduced sperm numbers and decreased sperm motility. [provided by MGI curators] |