| Primary Identifier | MGI:2675669 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 108907 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microtubule binding activity. Predicted to be involved in establishment of mitotic spindle localization; mitotic chromosome condensation; and mitotic cytokinesis. Predicted to act upstream of or within mitotic sister chromatid segregation and positive regulation of mitotic nuclear division. Located in nucleolus. Is active in mitotic spindle. Is expressed in several structures, including genitourinary system; gut; immune system; respiratory system; and skin. Orthologous to human NUSAP1 (nucleolar and spindle associated protein 1). PHENOTYPE: Early embryos homozygous for a knock-out allele are small and exhibit disorganized embryonic tissue, abnormal chromatin-induced spindle assembly, abnormal inner cell mass apoptosis, and complete embryonic lethality at implantation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
