| Primary Identifier | MGI:1919144 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 329502 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including phosphatidylinositol phosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and phospholipase A2 activity. Involved in N-acylphosphatidylethanolamine metabolic process and positive regulation of endocytic recycling. Located in early endosome membrane; lysosomal membrane; and plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PLA2G4E (phospholipase A2 group IVE). PHENOTYPE: Mice homozygous for a null allele exhibit decreased N-acylethanolamine-related lipids and increased susceptibility to imiquimod-induced skin inflammation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
