Primary Identifier | MGI:2685493 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 271844 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium-dependent phospholipase A2 activity and lysophospholipase activity. Acts upstream of or within several processes, including arachidonate secretion; cellular response to antibiotic; and prostaglandin biosynthetic process. Located in cytosol; ruffle membrane; and vesicle. Orthologous to human PLA2G4F (phospholipase A2 group IVF). PHENOTYPE: Lung fibroblasts from homozygous mutant mice show a normal response to the calcium ionophore A23187. [provided by MGI curators] |