| Primary Identifier | MGI:1270153 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 20402 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables SH3 domain binding activity and opioid peptide activity. Acts upstream of or within insulin receptor signaling pathway. Located in cytosol and membrane. Is expressed in several structures, including adipose tissue; central nervous system; esophagus; genitourinary system; and musculature. Used to study amyotrophic lateral sclerosis. Orthologous to human ZNF106 (zinc finger protein 106). PHENOTYPE: Mice homozygous for a null allele exhibit an abnormal gait, progressive motor deficits, kyphosis, weight loss, severe adult-onset degenerative sensory-motor axonopathy, mitochondrial dysfunction, and premature death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
