Primary Identifier | MGI:99441 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 12716 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable creatine kinase activity and identical protein binding activity. Involved in negative regulation of apoptotic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system; sensory organ; and urinary system. Orthologous to human CKMT1A (creatine kinase, mitochondrial 1A) and CKMT1B (creatine kinase, mitochondrial 1B). PHENOTYPE: Mice homozygous for a knock-out allele have no visual or motor impairments but display diminished open field habituation and slower spatial learning acquisition in the Morris water maze task as well as a reduced acoustic startle response, higher threshold, and lack of prepulse inhibition. [provided by MGI curators] |