Primary Identifier | MGI:1921651 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 74401 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in homologous chromosome pairing at meiosis and meiotic attachment of telomere to nuclear envelope. Acts upstream of or within meiosis I; oogenesis; and spermatogenesis. Located in chromosome, telomeric region and nuclear inner membrane. Human ortholog(s) of this gene implicated in spermatogenic failure 59. Orthologous to human TERB2 (telomere repeat binding bouquet formation protein 2). PHENOTYPE: Mice homozygous for a null allele exhibit sterility due to arrested meiosis. [provided by MGI curators] |