Primary Identifier | MGI:1889651 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 58521 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transcription corepressor activity. Predicted to be involved in cell differentiation and negative regulation of DNA-templated transcription. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleus. Predicted to be active in nucleoplasm. Is expressed in several structures, including heart; liver; lung; pancreas; and placenta. Orthologous to human EID1 (EP300 interacting inhibitor of differentiation 1). PHENOTYPE: Mice homozygous for a null allele exhibit lower neonatal survival rate, impaired spatial learning , smaller neonatal telencephalon volume, decreased neural stem cell proliferation rate. [provided by MGI curators] |