Primary Identifier | MGI:88170 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 109778 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables biliverdin reductase [NAD(P)+] activity. Predicted to be involved in heme catabolic process. Predicted to be active in cytosol. Is expressed in decidua; myometrium; placenta; and spongiotrophoblast. Orthologous to human BLVRA (biliverdin reductase A). PHENOTYPE: Mice homozygous for a null allele exhibit high mean erythrocyte cell number, increased mean corpuscular hemoglobin concentration, decreased mean corpuscular volume, decreased mean corpuscular hemoglobin, green gall bladder, yellow bile, bile composed of biliverdin rather than bilirubin, and increased endogenous oxidative stress. [provided by MGI curators] |