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Protein Coding Gene : Blvra biliverdin reductase A
Primary Identifier  MGI:88170 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  109778
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables biliverdin reductase (NAD(P)H) activity. Predicted to be involved in heme catabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in decidua; myometrium; placenta; and spongiotrophoblast. Orthologous to human BLVRA (biliverdin reductase A).
PHENOTYPE: Mice homozygous for a null allele exhibit high mean erythrocyte cell number, increased mean corpuscular hemoglobin concentration, decreased mean corpuscular volume, decreased mean corpuscular hemoglobin, green gall bladder, yellow bile, bile composed of biliverdin rather than bilirubin, and increased endogenous oxidative stress. [provided by MGI curators]
  • synonyms:
  • Blvr,
  • MGI:1917355,
  • MGI:1915580,
  • 0610006A11Rik,
  • MGD-MRK-1581,
  • RIKEN cDNA 2500001N03 gene,
  • biliverdin reductase A,
  • RIKEN cDNA 0610006A11 gene,
  • biliverdin reductase,
  • 2500001N03Rik,
  • Blvra
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2 Involved In Mutations

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

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Proteins

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Mouse features --> Functions (GO terms)

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Genes --> Homologs

Interactions

7 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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