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Protein Coding Gene : Dusp2 dual specificity phosphatase 2

Primary Identifier  MGI:101911 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  13537
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables mitogen-activated protein kinase binding activity and phosphoprotein phosphatase activity. Acts upstream of or within protein dephosphorylation. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system; dorsal root ganglion; and retina. Orthologous to human DUSP2 (dual specificity phosphatase 2).
PHENOTYPE: Homozygous mutation of this gene results in reduced inflammatory responses in induced rheumatoid arthritis. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-18740,
  • dual specificity phosphatase 2,
  • Dusp2,
  • PAC1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For