| Primary Identifier | MGI:2684962 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 215456 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 1-acylglycerol-3-phosphate O-acyltransferase activity and glycerol-3-phosphate O-acyltransferase activity. Involved in phosphatidic acid biosynthetic process and piRNA processing. Acts upstream of or within glycerol-3-phosphate metabolic process and triglyceride biosynthetic process. Located in mitochondrion. Is expressed in germ cell of testis; interstitium of the testis; testis; and tunica albuginea of testis. Orthologous to human GPAT2 (glycerol-3-phosphate acyltransferase 2, mitochondrial). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility associated with decreased testis weight, impaired spermatogenesis, azoospermia, abnormal DNA methylation during gametogenesis, and increased male germ cell apoptosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
