| Primary Identifier | MGI:1197519 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 12125 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microtubule binding activity and protein kinase binding activity. Involved in response to endoplasmic reticulum stress. Acts upstream of or within several processes, including apoptotic signaling pathway; hematopoietic or lymphoid organ development; and lymphocyte homeostasis. Located in membrane and mitochondrion. Part of Bcl-2 family protein complex. Is expressed in several structures, including hair outer root sheath; hemolymphoid system gland; metanephros; neural tube; and trunk mesenchyme. Orthologous to human BCL2L11 (BCL2 like 11). PHENOTYPE: Consistent with this gene's role in hematopoietic homeostasis, homozygous null mutants accumulate lymphoid and myeloid cells and succumb to autoimmune kidney disease. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
