Primary Identifier | MGI:97453 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 18429 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable V1A vasopressin receptor binding activity; neuropeptide hormone activity; and oxytocin receptor binding activity. Involved in positive regulation of cold-induced thermogenesis. Located in cytoplasm and extracellular region. Is expressed in brain. Orthologous to human OXT (oxytocin/neurophysin I prepropeptide). PHENOTYPE: Female homozygotes for targeted null mutations are unable to release milk for their suckling pups, while mutant males fail to develop social memory and are less aggressive. Both genders exhibit increased salt intake. [provided by MGI curators] |